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Metabolic dysfunction in ME/CFS not due to anti-mitochondrial antibodies
Metabolic dysfunction in myalgic encephalomyelitis/chronic fatigue syndrome not due to anti-mitochondrial antibodies, by Isabell Nilsson, Jeremy Palmer, Eirini Apostolou, Carl-Gerhard Gottfries, Muhammad Rizwan, Charlotte Dahle and Anders Rosén in Front. Med., 31 March 2020 [doi.org/10.3389/fmed.2020.00108 ] Research abstract: Metabolic profiling … Continue reading
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Tagged Adenosine triphosphate, Anders Rosén, autoreactive antibodies, blood lactate accumulation, Carl-Gerhard Gottfries, Charlotte Dahle, Eirini Apostolou, fatigue, Isabell Nilsson, Jeremy Palmer, mitochondrial dysfunction, Muhammad Rizwan, PBC, pDCs, Post-exertional malaise, primary biliary cholngitis, pyruvate dehydrogenase
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Roles of the right dorsolateral prefrontal cortex during physical fatigue: a magnetoencephalographic study
Research abstract: Background: A regulation system in the central nervous system plays an important role in controlling physical performance during physical fatigue. Purpose: To clarify the neural mechanisms of this regulation system during physical fatigue using magnetoencephalography (MEG) and a … Continue reading
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Tagged Central Nervous System, CNS, DLPFC, dorsolateral prefrontal cortex, fatigue, magnetoencephalography, Masaaki Tanaka, MEG
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Human herpesvirus 6 and 7 are biomarkers for fatigue
Research highlights: Salivary HHV-6 and HHV-7 can be used for assessment of physiological fatigue. Activation and differentiation of macrophages are needed for viral reactivation. Salivary HHV-6 and HHV-7 do not increase with pathological fatigue. Salivary HHV-6/7 can distinguish between physiological … Continue reading
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Tagged fatigue, HHV-6, HHV-7, human herpes virus-6, major depressive disorder, Obstructive Sleep Apnea Syndrome
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CoQ10 with NADH – potential treatment for fatigue in CFS
Research abstract: Background & aims: Chronic Fatigue Syndrome (CFS) is a complex condition, characterized by severe disabling fatigue with no known cause, no established diagnostic tests, and no universally effective treatment. Several studies have proposed symptomatic treatment with coenzyme Q10 … Continue reading
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Tagged Coenzyme Q10, CoQ10, fatigue, NADH, nicotinamide adenine dinucleotide, supplements
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Dr Jarred Younger interview about his neuroinflammation research
Cort Johnson interviews Dr Jarred Younger, head of the Neuroinflammation, Pain and Fatigue Lab at the University of Alabama at Birmingham about the neuroinflammation response in ME/CFS and FM, how to measure it and the types of anti-inflammatory drugs that … Continue reading
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Tagged Cort Johnson, cytokines, Dr Jarred Younger, fatigue, Fibromyalgia, FM, LDN, low dose naltrexone, lymphatic network, microglia, Neuroinflammation, pain
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Fatigue & depression levels higher in CFS than cancer
Research abstract: OBJECTIVE: Persistent fatigue and depressive symptoms are both highly prevalent among patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) as well as breast cancer survivors. This study aimed to assess and directly compare perceptions of fatigue as highly interfering … Continue reading
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Tagged cancer, cognitive behavioural therapy, Daniel L Hall, depression, Dr Nancy Klimas, fatigue
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Could change of diet help children with fatigue?
Research abstract: Many children deal with fatigue for which no proper treatment can be given. A possible explanation for their fatigue is a micro deficiency of minerals and vitamins. In this non-randomized controlled trial, we clinically evaluated symptoms of fatigue in … Continue reading
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Tagged children, diet, fatigue, micro-nutrients
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The nature of fatigue in CFS
Research abstract In this article, we report the findings of our study on the nature of fatigue in patients diagnosed with chronic fatigue syndrome. Using ethnoscience as a design, we conducted a series of unstructured interviews and card sorts to … Continue reading
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Tagged ethnosicence, exhaustion, fatigue, pacing, stress, tredness
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Are stamina and fatigue polar opposites?
Research abstract: Most individuals with Myalgic Encephalomyelitis/chronic fatigue syndrome (ME/CFS) (Carruthers et al., 2003), Myalgic Encephalomyelitis (ME) (Carruthers et al., 2011), and chronic fatigue syndrome (CFS) (Fukuda et al., 1994) indicate that they experience fatigue and sharp decreases in energy … Continue reading
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Tagged fatigue, Leonard A Jason, stamina
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Central pathways causing fatigue in CFS
Article abstract Background The genesis of severe fatigue and disability in people following acute pathogen invasion involves the activation of Toll-like receptors followed by the upregulation of proinflammatory cytokines and the activation of microglia and astrocytes. Many patients suffering from … Continue reading
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Tagged auto-immune, fatigue, neuro-inflammatory, oxidative stress, pro-inflammatory cytokines
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