Category Archives: News
B cell functional changes & Ca2+dysregulation in ME/CFS
Research abstract: Single nucleotide polymorphisms and genotypes of transient receptor potential ion channel and acetylcholine receptor genes from isolated B lymphocytes in myalgic encephalomyelitis/chronic fatigue syndrome patients, by Marshall-Gradisnik S, Johnston S , Chacko A , Nguyen T , Smith … Continue reading
Countess of Mar complains about BBC portrayal of FITNET trial
The Countess of Mar has written to the Director General of the BBC with a formal complaint about its portrayal of the FITNET trial from 1 Nov 2016 onwards. 3rd November 2016 Dear Lord Hall Formal Complaint to the BBC re: the purveying … Continue reading
Targeting serotonin and insulin-like growth factor in CFS
Thesis outline: Given the controversies and uncertainties surrounding these potentially important mediators in CFS, we decided to investigate the role of tryptophan, 5-HT and IGF-1 in CFS in this thesis. Our studies aim to obtain a deeper insight into the … Continue reading
Low putamen activity associated with poor reward sensitivity in childhood CFS
Research abstract: Mizuno K, Kawatani J, Tajima K, Sasaki AT, Yoneda T, Komi M, Hirai T, Tomoda A, Joudoi T, Watanabe Y. Low putamen activity associated with poor reward sensitivity in childhood chronic fatigue syndrome. Neuroimage Clin. 2016 Sep 26;12:600-606. eCollection 2016 … Continue reading
Support for the microgenderome invites enquiry into sex differences in ME/CFS
Research abstract: The microgenderome defines the interaction between microbiota, sex hormones and the immune system. Our recent research inferred support for the microgenderome by showing sex differences in microbiota-symptom associations in a clinical sample of patients with myalgic encephalomyelitis / … Continue reading
Robust evidence of an underlying biological process in ME/CFS
Miriam Tucker reports on the overwhelming evidence for the biological basis for ME/CFS which was presented at the IACFS/ME conference in the USA in October 2016: Biomarker Research Advances in ‘Chronic Fatigue Syndrome’, by Miriam E. Tucker in Medscape Medical … Continue reading
Investigation of the effects of vanilloids in animal model of chronic fatigue
Research abstract: AIM OF THE STUDY: To assess the effectiveness of TRPV1 modulators in animal model of Chronic fatigue syndrome (CFS). To assess central and peripheral behavioral activity of TRPV1 modulators. MATERIAL AND METHODS: CFS was induced by forcing the rats to … Continue reading
New Australian genetic marker detection study
ME Research UK blog post, 6 November 2016: New study – Genetic marker detection Prof Brett Lidbury and colleagues at the John Curtin School of Medical Research, Australian National University in Canberra are conducting an ongoing programme, funded by charities in … Continue reading
Hypothalamic-Pituitary-Adrenal Hypofunction in ME/CFS
Review abstract: There is evidence that immune-inflammatory and oxidative and nitrosative stress (O&NS) pathways play a role in the pathophysiology of myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS). There is also evidence that these neuroimmune diseases are accompanied by hypothalamic-pituitary-adrenal (HPA) axis … Continue reading
