Category Archives: News
A new approach for investigating mitochondrial DNA in ME
Research abstract: In mitochondrial research, many investigators have examined the association between mitochondrial DNA (mtDNA) variants in rare as well as common complex diseases. Previous studies at the CHM (NWU) detected three known pathogenic mtDNA variants (m.7497G>A, m.9185T>C and m.10197G>A) at … Continue reading
Complementary & alternative healthcare use by participants in PACE trial
Research abstract: Background: Chronic Fatigue Syndrome (CFS) is characterised by persistent fatigue, disability and a range of other symptoms. The PACE trial was randomised to compare four non-pharmacological treatments for patients with CFS in secondary care clinics. The aims of this sub study … Continue reading
More in-depth mitochondrial testing in ME/CFS proposed
Blog post by Cort Johnson in Health Rising forum, 20 June 2016: Researchers Call For More In-depth Mitochondrial Testing in Chronic Fatigue Syndrome (ME/CFS) More Extensive Mitochondrial Testing Proposed A letter to the editor of the BioMed Central Journal urged … Continue reading
CBT for CFS: differences in outcomes in the UK & Netherlands
Research abstract: Objective: Cognitive behaviour therapy (CBT) reduces fatigue and disability in chronic fatigue syndrome (CFS). However, outcomes vary between studies, possibly because of differences in patient characteristics, treatment protocols, diagnostic criteria and outcome measures. The objective was to compare outcomes after CBT in … Continue reading
The psychological impact of dependency in adults with CFS/ME
Research abstract: Chronic fatigue syndrome/myalgic encephalomyelitis can limit functional capacity, producing various degrees of disability and psychological distress. Semi-structured interviews explored the experiences of adults with chronic fatigue syndrome/myalgic encephalomyelitis being physically dependent on other people for help in daily … Continue reading
Altered neuroendocrine control in adolescent CFS
Research abstract: BACKGROUND: Chronic fatigue syndrome (CFS) is a common and disabling disorder, and a major threat against adolescent health. The pathophysiology is unknown, but alteration of neuroendocrine control systems might be a central element, resulting in attenuation of the … Continue reading
The role of stress in biological systems and chronic fatigue
Review highlights: • We review stress signal sensitivity of immune cells in chronic stress and fatigue. • Chronic stress seems to result in resistance of immune cells to stress signals. • Findings on stress signal sensitivity under acute stress were … Continue reading
Help improve info about raising a concern or complaint in NHS Wales
Putting Things Right leaflet – How to raise a concern or complaint about the NHS in Wales Gweithio i Wella – Sut i leisio pryder am y GIG yng Nghymru NHS Wales is reviewing the ‘Putting Things Right’ leaflet as part of … Continue reading
No difference found in difference in KIR expression in ME/CFS
Research abstract: Killer cell immunoglobulin-like receptor (KIR) genes encode for activating and inhibitory surface receptors, which are correlated with the regulation of Natural Killer (NK) cell cytotoxic activity. Reduced NK cell cytotoxic activity has been consistently reported in Chronic Fatigue … Continue reading
A potential biomarker for fatigue: oxidative stress & anti-oxidative activity
Research Highlights: Fatigue is a frequent symptom in both healthy individuals and patients, therefore, biomarkers indicating several differential levels of fatigue would be needed for evaluating fatigue and its improvement. Following the hard work term, the mean values of oxidative … Continue reading
