Category Archives: News

Effect on siblings of children with CFS/ME

Research abstract: Chronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME) is a disabling condition known to have a negative impact on all aspects of a child’s life. However, little is understood about the impact of CFS/ME on siblings. A total of … Continue reading

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Characteristics of CFS/ME sub-group who respond to Rintatolimod (Ampligen)

Research abstract: Background: Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is a debilitating disease of unknown pathogenesis consisting of  a variety of flu-like symptoms including severe fatigue. Initial analysis of the use of rintatolimod (Poly I: Poly C12U), a selective TLR3 agonist, … Continue reading

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UK rituximab trial fundraising total almost reached

Invest in ME has announced the latest fundraising total for the rituximab/B-cell research, which is a great boost as the research team at UCL are about to visit and discuss the subject with Dr Fluge and Professor Mella in Haukeland University Hospital, … Continue reading

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Elevated autoantibodies found in CFS subgroup

Research highlights: β adrenergic and muscarinic acetylcholine receptor autoantibodies are elevated in a subset of patients with Chronic Fatigue Syndrome (CFS). Elevated autoantibodies in CFS correlate with elevated IgG1-3 subclass levels, thyreoperoxidase and ANA antibodies and T cell activation. In … Continue reading

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Poor self-esteem found in adolescents with CFS

Research abstract: Background: The self and self-experience are often assumed to play an important role in adolescent patients presenting with severe somatic symptoms and bodily distress. Nonetheless, most empirical work on this subject is confined to studies of personality and … Continue reading

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Severity of POT fluctuates in ME

Research abstract: Central nervous system dysfunction with myalgic encephalomyelitis (ME) has been suggested as the main cause of chronic fatigue syndrome. Fluctuation of the symptom severity and hierarchy is a characteristic feature in ME patients. The characteristics of the sympathetic … Continue reading

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Seroxat study under-reported harmful effects on young people

Seroxat study under-reported harmful effects on young people, say scientists, by Sarah Boseley Health editor in Guardian online, Wednesday 16 September 2015 Experts who re-analysed data say study is still referred to in medical literature and needs to be retracted. An … Continue reading

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SSRI combined with Dengzhanshengmai improves fatigue

Research abstract: OBJECTIVE: This study was to assess the efficacy and safety of selective serotonin reuptake inhibitor (SSRI) plus Dengzhanshengmai capsule in patients with chronic fatigue syndrome (CFS). METHODS: SSRI at a moderate dose plus Dengzhanshengmai (n = 134) with … Continue reading

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Clonidine has little effect on autonomic cardiovascular & orthostatic symptoms in adolescents with CFS

Research abstract: Background: Chronic Fatigue Syndrome (CFS) is a common and disabling condition in adolescence with few treatment options. A central feature of CFS is orthostatic intolerance and abnormal autonomic cardiovascular control characterized by sympathetic predominance. We hypothesized that symptoms … Continue reading

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Measuring post exertional fatigue

Research abstract: OBJECTIVE: To design and validate an instrument to capture the characteristic post-exertional exacerbation of fatigue in patients with chronic fatigue syndrome (CFS). HIGHLIGHTS: Provides a new self-report measure of fatigue in patients with chronic fatigue syndrome Uniquely captures fatigue … Continue reading

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