Category Archives: News
Cognitive performance affected by poor muscle function in CFS & FM
Abstract BACKGROUND: Both good physical and cognitive functioning have a positive influence on the execution of activities of daily living. Patients with chronic fatigue syndrome (CFS) as well as patients with fibromyalgia have marked cognitive deficits. Furthermore, a good physical … Continue reading
Why ineffective psychotherapies appear to work
Article abstract: The past 40 years have generated numerous insights regarding errors in human reasoning. Arguably, clinical practice is the domain of applied psychology in which acknowledging and mitigating these errors is most crucial. We address one such set of errors … Continue reading
Methylation may have role in immunological changes in CFS/ME
Abstract Objective: Methylation is known to regulate biological processes and alterations in methylation patterns have been associated with a variety of diseases. Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is an unexplained disorder associated with immunological and molecular changes. CD4+T cells specifically, … Continue reading
Review of SNS dysfunction in Orthostatic Intolerance
Review abstract Orthostatic intolerance is the inability to tolerate the upright posture and is relieved by recumbence. It most commonly affects young women and has a major impact on quality of life and psychosocial well being. Several forms of orthostatic … Continue reading
Impaired range of motion found in teenagers with CFS
Abstract Objective To determine whether adolescents and young adults with chronic fatigue syndrome (CFS) have a greater prevalence of impaired range of motion (ROM) of the limbs and spine than healthy control patients. Study design Case-control study comparing rates of … Continue reading
Intracellular bacteria interfere with dendritic cell functions
Abstract Dendritic cells (DCs) orchestrate host defenses against microorganisms. In infectious diseases due to intracellular bacteria, the inefficiency of the immune system to eradicate microorganisms has been attributed to the hijacking of DC functions. In this study, we … Continue reading
SFPN (small-fiber polyneuropathy) found in children with pain syndromes
Abstract OBJECTIVE: We tested the hypothesis that acquired small-fiber polyneuropathy (SFPN), previously uncharacterized in children, contributes to unexplained pediatric widespread pain syndromes. METHODS: Forty-one consecutive patients evaluated for unexplained widespread pain beginning before age 21 had medical records … Continue reading
Characterisation of impaired NK cells in CFS/ME
Abstract OBJECTIVE Natural Killer (NK) cells are classified into different phenotypes according to the expression of the surface markers CD56 and CD16. Each NK cell phenotype has a role in the immune response through cytotoxic activity or cytokine production. Reduced … Continue reading
Is CFS an autoimmune disorder with vasoactive neuropeptide dysfunction?
Abstract Chronic fatigue syndrome is a disorder characterised by prolonged fatigue and debility and is mostly associated with post-infection sequelae although ongoing infection is unproven. Immunological aberration is likely and this may prove to be associated with an expanding group … Continue reading
‘Flowers’ in the blood – abnormally shaped red blood cells in CFS
CASE REPORT Abstract Introduction: Chronic fatigue syndrome is a debilitating condition characterized by persistent fatigue, post-exertional malaise, myalgia, arthralgia, lymph node tenderness, impaired memory and concentration, autonomic irregularities, and other specific symptoms affecting multiple body systems. Diverse hypotheses have been … Continue reading
