Tag Archives: biomarker

Research review: Biomarkers for ME/CFS

Posted on 05/25/2023 by wames

Biomarkers for ME/CFS: a systematic review   Australian researchers found 101 key studies in ME/CFS that varied in efficacy, quality, and potential to be developed into a diagnostic biomarker. Most were blood-based and measured a range of dysfunction. “Many of … Continue reading →

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Research: Distinguishing ME/CFS & FM

Posted on 02/23/2023 by wames

Distinguishing ME/CFS and FM through gene expression   Canadian researchers have measured the activity (expression) of genes in people with ME/CFS and Fibromyalgia. 3 of the 11 miRNA were over-expressed in ME/CFS and under-expressed in FM. These three miRNAs could … Continue reading →

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Research: Metabolomic evidence for peroxisomal dysfunction in ME/CFS

Posted on 07/27/2022 by wames

Metabolomic evidence for peroxisomal dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome   Research conclusion: Our findings provide the first metabolomic evidence of peroxisomal dysfunction, and are consistent with dysregulation of lipid remodeling and the tricarboxylic acid cycle. These findings, if validated … Continue reading →

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Biomarker research: Submaximal exercise provokes increased activation of the anterior DMN during the resting state as a biomarker of PEM in ME/CFS

Posted on 01/19/2022 by wames

Submaximal exercise provokes increased activation of the anterior default mode network during the resting state as a biomarker of postexertional malaise in Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome, by Rakib U Rayhan and  James N Baraniuk in Front. Neurosci., 15 Dec 2021 … Continue reading →

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Biomarker research: The maintained attention assessment in patients affected by ME/CFS

Posted on 12/09/2021 by wames

The maintained attention assessment in patients affected by Myalgic encephalomyelitis/ chronic fatigue syndrome: A reliable biomarker?, by Inigo Murga, Larraitz Aranburu, Pascual A Gargiulo, Juan-Carlos Gomez-Esteban, Jose-Vicente Lafuente in Journal of Translational Medicine Vol 19, #1, p 494, December 4, 2021 … Continue reading →

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Diagnostic test research: Saliva fatigue biomarker for severe ME/CFS

Posted on 11/10/2021 by wames

Saliva fatigue biomarker index as a marker for severe myalgic encephalomyelitis/ chronic fatigue syndrome in a community based sample, by Leonard A Jason, John Kalns, Alicia Richarte, Ben Z Katz, Chelsea Torres in Fatigue: Biomedicine, Health & Behavior, October 27, 2021 … Continue reading →

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Biomarker research: The case for hyperbaric oxygen therapy in CFS biomarker identification

Posted on 08/25/2021 by wames

Chronic fatigue syndrome and epigenetics: the case for hyperbaric oxygen therapy in biomarker identification, by Rajit J Shah in J Pulmonol Respir Res. 2021; 5: 027-030. [DOI: 10.29328/journal.jprr.1001020]   Review abstract: Chronic fatigue syndrome (CFS) is a poorly-understood respiratory condition that … Continue reading →

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Biomarker research: Skewing of the B cell receptor repertoire in ME/CFS

Posted on 07/09/2021 by wames

Skewing of the B cell receptor repertoire in myalgic encephalomyelitis/ chronic fatigue syndrome, by Wakiro Sato, Hirohiko Ono, Takaji Matsutani, Masakazu Nakamura, Isu Shin, Keiko Amano, Ryuji Suzuki, Takashi Yamamura in Brain, Behavior, and Immunity, Vol 95, July 2021, Pages 245-255 … Continue reading →

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Insights into metabolite diagnostic biomarkers for ME/CFS

Posted on 04/13/2021 by wames

Insights into metabolite diagnostic biomarkers for Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome, by Emi Yamano, Yasuyoshi Watanabe and Yosky Kataoka in Int. J. Mol. Sci. 2021, 22(7), 3423; [doi.org/10.3390/ijms22073423] 26 March 2021 (This article belongs to the Special Issue Environmental Sensitivity Illnesses: … Continue reading →

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Sex-based differences in plasma autoantibodies to CNS proteins in Gulf War veterans versus healthy & symptomatic controls

Posted on 02/22/2021 by wames

Sex-based differences in plasma autoantibodies to Central Nervous System proteins in Gulf War veterans versus healthy and symptomatic controls, by Mohamed B Abou-Donia, Maxine H Krengel, Elizabeth S Lapadula, Clara G Zundel, Jessica LeClair, Joseph Massaro, Emily Quinn, Lisa A … Continue reading →

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