Author Archives: wames
Perturbation of effector & regulatory T cell subsets in ME/CFS
Perturbation of effector and regulatory T cell subsets in Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS), by Ece Karhan, Courtney Gunter, Vida Ravanmehr, Meghan Horne, Lina Kozhaya, Stephanie Renzullo, Lindsey Placek, Joshy George, Peter N Robinson, Suzannne D Vernon, Lucinda Bateman, … Continue reading
Autonomic markers, CFS & post-exertion states
Autonomic markers, chronic fatigue syndrome, and post-exertion states, by Fred Friedberg in Journal of Psychosomatic Research Vol 127, Dec 2019, [https://doi.org/10.1016/j.jpsychores.2019.109845] Article extracts: A large body of evidence suggests that autonomic imbalance, i.e., hyperactive sympathetic nervous system and hypoactive … Continue reading
Patients with ME/CFS & chronic pain report similar level of sickness behavior as individuals injected with bacterial endotoxin at peak inflammation
Patients with ME/CFS (Myalgic Encephalomyelitis/Chronic Fatigue Syndrome) and chronic pain report similar level of sickness behavior as individuals injected with bacterial endotoxin at peak inflammation, by Martin A Jonsjö, Jenny Åström, Michael P Jones, Bianka Karshikoff, KarinLodin, Linda Holmström, Lars Agréus, … Continue reading
Central sensitization: a pathogenic mechanism in complex undefined diseases
Central sensitization: A pathogenic mechanism in complex undefined diseases, by Joaquim Fernández-Solà, in Neuropsychiatry (London) 2019: 9(6), 2485–2490 Abstract: There is a common perception that complex undefined diseases manifested with diverse combination of symptoms and a difficult clinical diagnosis have … Continue reading
An investigation into the modulation of T cell phenotypes by amitriptyline & nortriptyline
An investigation into the modulation of T cell phenotypes by amitriptyline and nortriptyline, by JonathanRoyds, Melissa J Conroy, Margaret R Dunne, Connail McCrory, Joanne Lysaght in European Neuropsychopharmacology, Dec 2019[doi.org/10.1016/j.euroneuro.2019.12.106] Research abstract: Amitriptyline is prescribed for treating the symptoms … Continue reading
Register your interest today in taking part in ME/CFS genome-wide research!
The ME/CFS Biomedical Partnership Genome-wide association study The ME/CFS Biomedical Partnership is working on a funding application to be made in early 2020 to the MRC/NIHR for a genome-wide association study. How can we help? They need to demonstrate … Continue reading
WAMES helpline holiday hours 2019-2020
WAMES helpline hours The WAMES helpline is run by volunteers and will be closed over the festive period. We apologise that due to extra pressures on the team in January, the closure will last longer than usual. Feel free … Continue reading
Minireview for CFS & its medical attention recently
Minireview for Chronic Fatigue Syndrome and its medical attention recently, by Chang-Gue Son in J Korean Med. 2019;40(4):84-90 [http://dx.doi.org/10.13048/jkm.19043] Review abstract: Objectives: Chronic fatigue syndrome (CFS) is a debilitating illness impairing seriously quality of life, while CFS would be … Continue reading
Transient receptor potential melastatin 2 channels are overexpressed in ME/CFS patients
Transient receptor potential melastatin 2 channels are overexpressed in myalgic encephalomyelitis/chronic fatigue syndrome patients, by Cassandra Balinas, Helene Cabanas, Donald Staines, Sonya Marshall-Gradisnik in Journal of Translational Medicine Vol 17, #1, p 401, December 3, 2019 Research abstract: Background: Myalgic … Continue reading
Paediatric CFS patients’ & parents’ perceptions of recovery
Paediatric chronic fatigue syndrome patients’ and parents’ perceptions of recovery, by Matthew Robert Harland, Roxanne Morin Parslow, Nina Anderson, Danielle Byrne, Esther Crawley in BMJ Paediatrics Open Vol 3, #1, Dec 2, 2019 Research abstract: What is known about the … Continue reading