Category Archives: News
Characteristics of CFS/ME sub-group who respond to Rintatolimod (Ampligen)
Research abstract: Background: Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is a debilitating disease of unknown pathogenesis consisting of a variety of flu-like symptoms including severe fatigue. Initial analysis of the use of rintatolimod (Poly I: Poly C12U), a selective TLR3 agonist, … Continue reading
UK rituximab trial fundraising total almost reached
Invest in ME has announced the latest fundraising total for the rituximab/B-cell research, which is a great boost as the research team at UCL are about to visit and discuss the subject with Dr Fluge and Professor Mella in Haukeland University Hospital, … Continue reading
Elevated autoantibodies found in CFS subgroup
Research highlights: β adrenergic and muscarinic acetylcholine receptor autoantibodies are elevated in a subset of patients with Chronic Fatigue Syndrome (CFS). Elevated autoantibodies in CFS correlate with elevated IgG1-3 subclass levels, thyreoperoxidase and ANA antibodies and T cell activation. In … Continue reading
Poor self-esteem found in adolescents with CFS
Research abstract: Background: The self and self-experience are often assumed to play an important role in adolescent patients presenting with severe somatic symptoms and bodily distress. Nonetheless, most empirical work on this subject is confined to studies of personality and … Continue reading
Severity of POT fluctuates in ME
Research abstract: Central nervous system dysfunction with myalgic encephalomyelitis (ME) has been suggested as the main cause of chronic fatigue syndrome. Fluctuation of the symptom severity and hierarchy is a characteristic feature in ME patients. The characteristics of the sympathetic … Continue reading
Seroxat study under-reported harmful effects on young people
Seroxat study under-reported harmful effects on young people, say scientists, by Sarah Boseley Health editor in Guardian online, Wednesday 16 September 2015 Experts who re-analysed data say study is still referred to in medical literature and needs to be retracted. An … Continue reading
SSRI combined with Dengzhanshengmai improves fatigue
Research abstract: OBJECTIVE: This study was to assess the efficacy and safety of selective serotonin reuptake inhibitor (SSRI) plus Dengzhanshengmai capsule in patients with chronic fatigue syndrome (CFS). METHODS: SSRI at a moderate dose plus Dengzhanshengmai (n = 134) with … Continue reading
Clonidine has little effect on autonomic cardiovascular & orthostatic symptoms in adolescents with CFS
Research abstract: Background: Chronic Fatigue Syndrome (CFS) is a common and disabling condition in adolescence with few treatment options. A central feature of CFS is orthostatic intolerance and abnormal autonomic cardiovascular control characterized by sympathetic predominance. We hypothesized that symptoms … Continue reading
Measuring post exertional fatigue
Research abstract: OBJECTIVE: To design and validate an instrument to capture the characteristic post-exertional exacerbation of fatigue in patients with chronic fatigue syndrome (CFS). HIGHLIGHTS: Provides a new self-report measure of fatigue in patients with chronic fatigue syndrome Uniquely captures fatigue … Continue reading
Low NK cell activity differs in ME/CFS & MS
Research abstract: Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) and Multiple Sclerosis (MS) patients suffer from debilitating fatigue which is not alleviated by rest. In addition to the fatigue related symptoms suffered by CFS/ME and MS patients, dysfunction of the immune system … Continue reading
