Tag Archives: Prof Donald Staines

Decreased connectivity & increased BOLD complexity in the default mode network in CFS

Posted on 11/22/2017 by wames

Research abstract: Decreased connectivity and increased BOLD complexity in the default mode network in individuals with chronic fatigue syndrome, by ZY Shan, K Finegan, S Bhuta, T Ireland, DR Staines, SM Marshall-Gradisnik, LR Barnden in Brain Connect. 2017 Nov 20 … Continue reading →

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Medial prefrontal cortex deficits correlate with unrefreshing sleep in patients with CFS

Posted on 07/13/2017 by wames

Research abstract: Medial prefrontal cortex deficits correlate with unrefreshing sleep in patients with chronic fatigue syndrome, by Zack Y. Shan, Richard Kwiatek, Richard Burnet, Peter Del Fante,  Donald R. Staines, Sonya M. Marshall-Gradisnik and Leighton R. Barnden in NMR in Biomedicine [Published online: 29 JUN 2017] Unrefreshing … Continue reading →

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Australian researchers discover abnormalities in immune cell receptors in ME/CFS

Posted on 02/23/2017 by wames

Huffington Post Australia, by Luke Cooper, 22 Feb 2017: Queensland Scientists Make Chronic Fatigue Syndrome Research Breakthrough The condition has been linked to abnormal immune system cells. Queensland scientists have linked Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis … Continue reading →

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Review of dietary & nutrition interventions for CFS/ME

Posted on 02/08/2017 by wames

Review abstract: Background: Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is characterised by unexplained fatigue for at least 6 months accompanied by a diverse but consistent set of symptoms. Diet modification and nutritional supplements could be used to improve patient outcomes, such … Continue reading →

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A targeted genome association study examining transient receptor potential ion channels, acetylcholine receptors, and adrenergic receptors

Posted on 11/28/2016 by wames

Research abstract: BACKGROUND: Chronic Fatigue Syndrome, also known as Myalgic Encephalomyelitis (CFS/ME) is a debilitating condition of unknown aetiology. It is characterized by a range of physiological effects including neurological, sensory and motor disturbances. This study examined candidate genes for … Continue reading →

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B cell functional changes & Ca2+dysregulation in ME/CFS

Posted on 11/16/2016 by wames

Research abstract: Single nucleotide polymorphisms and genotypes of transient receptor potential ion channel and acetylcholine receptor genes from isolated B lymphocytes in myalgic encephalomyelitis/chronic fatigue syndrome patients, by Marshall-Gradisnik S, Johnston S , Chacko A , Nguyen T , Smith … Continue reading →

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Calcium mobilisation in natural killer cells & cell cytotoxicity in CFS/ME

Posted on 10/17/2016 by wames

Research abstract: Transient receptor potential melastatin subfamily 3 (TRPM3) ion channels play a role in calcium (Ca2+ ) cell signalling. Reduced TRPM3 has been identified in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) patients. However, the significance of TRPM3 and association with … Continue reading →

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Dysregulation of protein kinase gene expression in NK Cells in CFS

Posted on 09/12/2016 by wames

Research abstract: BACKGROUND: The etiology and pathomechanism of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) are unknown. However, natural killer (NK) cell dysfunction, in particular reduced NK cytotoxic activity, is a consistent finding in CFS/ME patients. Previous research has reported significant changes … Continue reading →

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Protein kinase gene dysfunction in severe CFS/ME

Posted on 08/30/2016 by wames

Research abstract: Background: The etiology and pathomechanism of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) are unknown. However, natural killer (NK) cell dysfunction, in particular reduced NK cytotoxic activity, is a consistent finding in CFS/ME patients. Previous research has reported significant changes … Continue reading →

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Mast cell dysfunction in ME/CFS

Posted on 07/11/2016 by wames

Research abstract: BACKGROUND: Mast cells (MCs) mediate inflammation through neuropeptides and cytokines, along with histamine and reactive oxygen species (ROS). Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is an illness characterized by an unexplained disabling fatigue with multiple physiological impairments as well as … Continue reading →

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