Category Archives: News

A neuro-inflammatory model can explain the onset, symptoms and flare-ups of ME/CFS

A neuro-inflammatory model can explain the onset, symptoms and flare-ups of myalgic encephalomyelitis/chronic fatigue syndrome, by Angus Mackay in Journal of Primary Health Care 11(4) 300-307 2019 [https://doi.org/10.1071/HC19041]   Abstract: A neuro-inflammatory model is proposed to explain the onset, symptoms … Continue reading

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Paediatric patients with ME/CFS value understanding & help to move on with their lives

Paediatric patients with myalgic encephalomyelitis/chronic fatigue syndrome value understanding and help to move on with their lives, by Katherine Rowe in Acta Paediatrica, First published: 18 December 2019 [https://doi.org/10.1111/apa.15054]   Abstract: Aim: The aim of this study was to document … Continue reading

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The role of low-grade inflammation in ME/CFS – associations with symptoms

The role of low-grade inflammation in ME/CFS (Myalgic Encephalomyelitis/Chronic Fatigue Syndrome) – associations with symptoms, by Martin A Jonsjö, Gunnar L Olsson, Rikard K Wicksell, Kjell Alving, Linda Holmström, Anna Andreasson in Psychoneuroendocrinology Vol 113, March 2020, 104578 [https://doi.org/10.1016/j.psyneuen.2019.104578]   Highlights … Continue reading

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The All-Party Parliamentary Group on ME to re-convene – Please invite your MP to attend!

ME Association blog post: The All-Party Parliamentary Group on ME to Re-Convene – Please Invite Your MP to Attend! by Dr Charles Shepherd, 9 January 2020 Carol Monaghan MP has decided that the time is right to re-establish the APPG on … Continue reading

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Perturbation of effector & regulatory T cell subsets in ME/CFS

Perturbation of effector and regulatory T cell subsets in Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS), by Ece Karhan, Courtney Gunter, Vida Ravanmehr, Meghan Horne, Lina Kozhaya, Stephanie Renzullo, Lindsey Placek, Joshy George, Peter N Robinson, Suzannne D Vernon, Lucinda Bateman, … Continue reading

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Autonomic markers, CFS & post-exertion states

Autonomic markers, chronic fatigue syndrome, and post-exertion states, by Fred Friedberg in Journal of Psychosomatic Research Vol 127, Dec 2019, [https://doi.org/10.1016/j.jpsychores.2019.109845]   Article extracts: A large body of evidence suggests that autonomic imbalance, i.e., hyperactive sympathetic nervous system and hypoactive … Continue reading

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Patients with ME/CFS & chronic pain report similar level of sickness behavior as individuals injected with bacterial endotoxin at peak inflammation

Patients with ME/CFS (Myalgic Encephalomyelitis/Chronic Fatigue Syndrome) and chronic pain report similar level of sickness behavior as individuals injected with bacterial endotoxin at peak inflammation, by Martin A Jonsjö, Jenny Åström, Michael P Jones, Bianka Karshikoff, KarinLodin, Linda Holmström, Lars Agréus, … Continue reading

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Central sensitization: a pathogenic mechanism in complex undefined diseases

Central sensitization: A pathogenic mechanism in complex undefined diseases, by Joaquim Fernández-Solà, in Neuropsychiatry (London) 2019: 9(6), 2485–2490   Abstract: There is a common perception that complex undefined diseases manifested with diverse combination of symptoms and a difficult clinical diagnosis have … Continue reading

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An investigation into the modulation of T cell phenotypes by amitriptyline & nortriptyline

An investigation into the modulation of T cell phenotypes by amitriptyline and nortriptyline, by JonathanRoyds, Melissa J Conroy, Margaret R Dunne, Connail McCrory, Joanne Lysaght in European Neuropsychopharmacology, Dec 2019[doi.org/10.1016/j.euroneuro.2019.12.106]   Research abstract: Amitriptyline is prescribed for treating the symptoms … Continue reading

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Register your interest today in taking part in ME/CFS genome-wide research!

The ME/CFS Biomedical Partnership Genome-wide association study The ME/CFS Biomedical Partnership is working on a funding application to be made in early 2020 to the MRC/NIHR for a genome-wide association study.   How can we help? They need to demonstrate … Continue reading

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