Category Archives: News
Immune dysfunction differs in moderate and severe CFS/ME over time
Research abstract: Background: Research has identified immunological abnormalities in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME), a heterogeneous illness with an unknown cause and absence of diagnostic test. There have been no CFS/ME studies examining innate and adaptive immune cells longitudinally in … Continue reading
Childhood trauma in CFS: personality disorders & psychopathology
Research abstract: INTRODUCTION: Personality Disorders (PDs) and childhood traumatic experiences have been considered risk factors for Chronic Fatigue Syndrome (CFS). However, the relationship between these factors and their associated psychopathological impact has not been explored in this population. This study … Continue reading
Orthostatic intolerance syndromes have different biochemical, autonomic and hemodynamic parameters
Research abstract: INTRODUCTION AND OBJECTIVES: Orthostatic intolerance (OI) syndromes are a confusing topic and determining a specific diagnosis to achieve optimal treatment can be troublesome. We sought to assess biomarker, hemodynamic and autonomic variables in OI patients (autonomic dysfunction [AD], … Continue reading
KPAX002 (Ritalin & micronutrients) well tolerated & effective for some CFS patients
Abstract: Stimulant drugs and various micronutrient interventions have previously been studied in chronic fatigue syndrome (CFS) but they have never been studied in combination. This proof of concept investigation seeks to examine the clinical effects and safety profile of KPAX002 … Continue reading
Activity pacing (APT) self management approach for CFS
Research abstract: OBJECTIVE: The objective of this study was to evaluate the effectiveness of an activity pacing self-management (APSM) intervention in improving performance of daily life activities in women with chronic fatigue syndrome (CFS). METHOD: A total of 33 women … Continue reading
Poor quality of life in young people with ME/CFS
An ME Research UK article comments on the recent research in Norway into adolescents with CFS: For such a devastating illness, there is surprisingly little information in the scientific literature about patients’ experiences of living with ME/CFS day-to-day. The few … Continue reading
No reduction of severe fatigue in Post Polio Syndrome by exercise therapy or CBT
Research abstract: BACKGROUND: People with postpolio syndrome (PPS) commonly experience severe fatigue that persists over time and negatively affects functioning and health-related quality of life (HRQoL). OBJECTIVES To study the efficacy of exercise therapy (ET) and cognitive behavioral therapy (CBT) … Continue reading
COMT gene dysfunction linked to susceptibility to infection in CFS
Research abstract: BACKGROUND: Chronic fatigue syndrome (CFS) is considered as a neuroimmunological disease but the etiology and pathophysiology is poorly understood. Patients suffer from sustained exhaustion, cognitive impairment and an increased sensitivity to pain and sensory stimuli. A subset of … Continue reading
Fluctuations in CFS symptoms affects ability to remember them reliably
An earlier study by these researchers concluded that time frame, symptom stability, and momentary severity appear to influence reliability in reporting ME/CFS symptoms. These factors must be taken into account, because “[a]ccurate and reliable assessment is a crucial first step … Continue reading
Evaluation of the UK’s first NHS generic fatigue clinic
Research abstract: Importance: Fatigue is a significant and debilitating symptom affecting 25% of the population. It occurs in those with a range of chronic diseases, can be idiopathic and in 0.2–0.4% of the UK population occurs in combination with other … Continue reading
